Neurotransmitter Table
|
Neuro transmitter |
Receptor Subtype |
Location/Function/Effects/symptoms of excess or deficit if applicable |
Distribution (ie: CNS/PNS, GI, vascular) |
Drug classes that target this neurotransmitter or receptor |
Specific medications that target this neurotransmitter or receptor |
|
Glutamate |
AMPA |
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|
NMDA |
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|
GABA |
GABA a |
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|
GABA b |
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|
Serotonin 5HT |
5HT 1a |
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|
5HT 1B |
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|
5HT 1d |
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|
5HT 1E |
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|
5HT 1F |
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|
5HT 2A |
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|
5HT2B |
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|
5HT 2C |
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|
5HT 3 |
Ligand gated ion channels. highest levels in the brain stem- Targets: decreases nausea/emesis Will inhibit the release of NE and Ach- Targets: cognition, anxiety, addiction. |
CNS (chemoreceptor trigger zone) PNS: GI tract (vagal nerve) |
Antiemetics Antidepressants |
Antiemetics: ondansetron, granisetron, dolasetron, palonosetron Antidepressants: Mirtazapine vortioxetine |
|
|
5HT 4 |
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|
5HT 5 AB |
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|
5HT6 |
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|
5HT 7 |
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|
NE norepinephrine |
α 1 |
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|
α 2 |
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|
DA Dopamine |
D1 |
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|
D2 |
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|
D3 |
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|
D4 |
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|
Ach Acetylcholine |
Muscarinic |
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|
Nicotinic |
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|
Histamine |
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|
Melatonin |
1. For each neurotransmitter and receptor type, complete the following columns:
a. Location/function/effects/symptoms of excess or deficit
b. Distribution
c. Drug classes that target this neurotransmitter or receptor
d. All neurotransmitters and receptor types: Specific medications that target this neurotransmitter or receptor
2. This criterion is linked to a Learning Outcome Organization
3. Font is consistent throughout table, and grammar, spelling, and/or punctuation are accurate.
A total of 4 references needed with intext citation. 2 references provided below. Please use 7th edition APA scholarly references that are witin 5 years.
Stahl, S.M. (2020). Stahl’s essential psychopharmacology: Prescribers guide (7th ed.). Cambridge University Press.
Stahl, S. M. (2021). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (5th ed.). Cambridge University Press.
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